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Contrave is looking very promising for those seeking a diet pill that works. The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the main benefit of the drug outweighs the chance of a possible surge in blood pressure. Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you need to err to the side of caution and let the FDA do its job and demand some research be done so that the public knows the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say almost anything to keep people on their medications. Researchers discovered that participants using this drug for any year, lost weight within 4 weeks and have kept the weight off during the entire 56 weeks from the study. Contrave is really a combination with the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs that are made up of many active ingredient, which may make them far better and safer. Combo-pilling could be the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills has become popular could be the fact that as of right now there are not any long term prescription weightloss pills that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures certainly are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug also can raise blood pressure and pulse rate, and really should not be used in people who have a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and heartbeat and must 't be used in patients with uncontrolled high blood pressure, and also by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients having a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients on the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking. "This is the first drug I'm alert to that targets both the appetite and reward centres inside brain," he said.